Mill Hill has released a series of sequences from patients in Ukraine. Four of the samples had the receptor binding domain change D225G. Three samples were from lung, one from a throat swab.
Samples with D255G are listed below
A/Lviv/N6/2009
A/Lviv/N2/2009
A/Ternopil/N11/2009
A/Ternopil/N10/2009
All HA samples also had a Ukraine specific marker that had been previously found in swine.
More detailed analysis to follow.
http://www.recombinomics.com/News/11180902/Ukraine_D225G_Confirmed.html
Recombinomics Commentary 19:17
November 17, 2009
1,457,564 Influenza/ARI
83,526 Hospitalized
328 Deaths
The above numbers are in the latest update from the Ukraine Health Department and include 13 more deaths. Although the number of deaths has decline slightly from the prior two days, the increase in cases and hospitalizations suggest the decline in deaths may be temporary. The largest increase in cases was again in Kiev (5522 to 109,676) and two other eastern oblast (see map) had daily increases of more than 4000 cases (Dnipropetrovsk and Denetsk). The steady rise in deaths continues to increase concerns over an H1N1 genetic change leading to an increase in lung disease such as those described earlier.
WHO came out with a situation update which provided little specific information beyond earlier reports that the H1N1 did not have large changes. However, the new update did indicate that WHO regional centers in London and Atlanta were still investigating isolates, suggesting there have been sequences changes that are not fully characterized.
Recently released swine H1N1 from other locations have included receptor binding domain changes at position 225 (D225E, D225N, D225G) as well as 226 (Q226R) raising concerns that similar changes in Ukraine cold lead to the high frequency of fatal lung infections (Q226R has been seen previously in human H5N1 as well as H3 isolates from swine, ducks, and seals). The new update did not address receptor binding domain changes or other SNPs that could have significant effects on the pathogenicity of the virus.
Therefore, the release of sequences and comments on receptor binding domain changes would be useful.
U.S. health authorities have made pregnant women one of the highest priority groups for getting the H1N1 swine flu vaccine, but is it actually safe for pregnant women and their babies? Well, the truth is that miscarriage reports from pregnant women who have taken the H1N1 swine flu vaccine are starting to pour in from all over the nation. Vaccines and pregnancy simply do not mix safely. In fact, the package inserts for the swine flu vaccines actually say that the safety of these vaccines for pregnant women has not been established.
What you are about to read below should shock and anger you. If they are telling us that the swine flu vaccine is not safe for children under 6 months of age, then why in the world would it be safe for pregnant women and their babies? That doesn’t make an ounce of sense, does it?
The following H1N1 swine flu vaccine miscarriage horror stories are from a June 2010 birth club…..
EBWashington:
I am so upset. I was so excited to be pregnant after trying for a year. As soon as I found out I was pregnant, I joined this birth club and I was due June 25th. We have two healthy boys with no history of miscarriage. Everything was going great. Last Monday, I got the H1N1 vaccine thimerosal reduced (mercury reduced for pregnant women). On Tuesday morning, I started cramping and on Wednesday I started bleeding heavily. My hcg was 50 on Wednesday and I was almost 6 weeks along so it was low. They still thought that I might be pregnant but on Friday my hcg was down to 22. I am an emotional wreck. I feel like I had a healthy baby and I caused this by getting the H1N1 vaccine. My doctors pushed it. I researched online and there have been many miscarriages after the H1N1 vaccine but they haven’t been reported since it is hard to say what caused the miscarriages. I hope that I did not cause this. I wish everyone the best.
Tayla08
I don’t have an answer for you, but a friend of a friend just had a miscarriage 2-3 days after getting the shot. She was 7weeks. She had no previous history of m/c… No one can answer if they’re related…it hasn’t been out long enough and there haven’t been any studies done on pregnant women. I will tell you, that it has made up my mind on getting it…I won’t and I’m not going to get it for my DD either. My daughter and I both had H1N1 last week, and although it truly sucks…I think I’ll take my chances. One doctor will tell you to get it and the next will tell you not too…you have to do what’s in your heart.
90707
my heart goes out to you as i recently miscarried as well and was due in june. i had a healthy heart beat at 6wks. then at 7.5 wks my son got the h1n1 mist vaccine which has live vaccine in it. the nurse said to be careful b/c it could technically spread if he rubbed his nose and touched a surface etc. the next night i miscarried and 5 days later was diagnosed with h1n1. i work from home, kids are home, hadnt been anywhere during that time. so the chances that it is all related are very high. the flu mist vaccine warns for immunocompromised patients (which includes prego) to stay away from recipients of the flu mist for 21 days.
This next set of H1N1 swine flu vaccine miscarriage horror stories is from an About.com page about miscarriage…..
Jo:
I got the flu vaccine (regular not H1N1) at 8 weeks pregnant. Three days later I miscarried. I am not going to get the H1N1.
Regrets:
I got both vaccines on Thursday. I was 9 weeks pregnant. I miscarried on Sunday. I was told by several doctors to get these vaccines. Now I wish I followed my gut feeling and not get them at ALL!
:
i work in a hospital like setting and was told ‘the benefits outweigh the risks” 1am i got the vaccine, 3am i started bleeding and craming, 3pm miscarried. you decide
sue:
I had the H1N1 vaccination and 24 hours later had a miscarriage.
Linda Hill:
My daughter in law was 10 weeks pregnant and had the H1N1 vaccine on Friday that night she miscarried.
SoSorry:
I was so ready to get the H1N1 vaccine last week and they were only giving them to pregnant women. I was 6 weeks along and got it and the next day I started cramping and miscarried. I already had two healthy pregnancies and never miscarried or had any problems. My doctors think I am crazy to think it was the H1N1 but if no one looks into this than other women will not know. I am so sorry that I got it.
Connie:
I also received the H1N1 vaccination on October 22nd, 2009 and went into labor on October 25th, at 16 weeks pregnant and we just heard the heartbeat and everything was fine with my pregnancy on October 16th, 2009, then on October 28th my water broke then on October 29th, I delivered a stillborn baby boy, and no one can tell me why…Everyone wants to say it did not come from the shot but I believe it did. My baby was growing at the correct pace and everyone wants to brush off the vaccination. I say if you have the vaccination and suffer a miscarriage if they are able to perform an autopsy have it done.
I also agree something needs to be done and looked more into with this vaccination because most women are being advised it’s just something that happens, but I also had two healthy children normal pregnancies and when I received this vaccination with my third pregnancy, my baby is gone.
sioux falls, south dakota:
I received the H1N1 vaccine on October 16th and started experiencing cramping on the 22nd. I was nearly 17 weeks pregnant and gave birth to a stillborn baby boy on the 23rd. Like many of the other women here, the first thing I suspected was the H1N1 vaccine. I immediately asked a nurse at the hospital if that would have anything to do with it. Without hesitation, she told me “absolutely not.” I had reservations about getting the vaccine, but followed the advice of my long trusted family doctor. In a follow up appointment with my doctor 3 days after I lost my baby, I asked him if the vaccine would have had any adverse effects on my baby. He also said that it was not possible. I don’t believe that my doctor was necessarily lying to me, he was simply following the accepted practices and opinions of his field. I do, however, believe that as a nation, we are being lied to. This vaccine is NOT safe during pregnancy. There has not been enough testing done to determine this and there are far too many “coincidences” for this to be anything but a result of a vaccine that was hastily pushed into production and distribution in an effort to stop widespread panic. I have read so many stories in defense of the vaccine that will talk about how common miscarriages are, but I would challenge you to ask ANY health care professional how common second trimester miscarriages are. My baby was doing perfect developmentally and I had felt him move earlier that day. My heart goes out to all of you out there who have had to go through the same heartache and loss that I have had in the last couple of weeks. There is no reason that any woman or family should have to go through this. Get the word out to all of the pregnant women that you know. I know that if I had heard that women had been losing their babies shortly after they received the vaccine, I would have followed my gut and not gotten it myself. Maybe then Wyatt would have had a chance at life.
Marina Rossi:
I recently got the H1N1 vaccine and miscarried 3 days later. I thought it could have been the vaccine but didnt ask. After finding this site I believe it was the vaccine. Sorry to everyone else out there who has just experienced a miscarriage.
kathy-sd:
I’m from a town of 2000 in SD, there are several women pregnant and we are all due within a few weeks of each other. Four of us got the H1N1 vaccine 2 weeks ago and one by one each of us started to have preterm contractions. We are all due in Nov and Dec so we are further along than most of the people that lost their babies. There is no way you can tell us that our preterm labor was not caused by the H1N1 vaccine. It may look like a “fluke” to some people when these women are scattered all over the country but we are talking about 4 of us in our small community. My heart goes out to all of you that lost your babies.
ashley:
Im not sure but not only myself, i know someone that withing 4 days of getting the shot we both miscarried, i was only 6 weeks and she was 4 months along, not sure if the shot caused it and cant find any other information but i am a little concerned about this coincidence.
Time Machine:
I got a flu shot in pregnancy, developed incredibly strange symptoms immediately (numb hands, feet and mouth, heart palpitations, sudden weakness in my legs, a bright red face), began bleeding and miscarried by 11 weeks. I had no idea there was mercury in most flu shots but once I found out after the fact, I was assured that I’d had the “mercury free” form. As it turned out, the shot wasn’t completely mercury free and, according to the EPA website, it still had 5,000 times the limit for mercury in drinking water– not to mention a list of other toxins (MSG, formaldehyde, etc.).
I’d had no idea the shots were so dirty. I guess I’d been under the impression they were something like sterile water and a dead virus, that’s it.
The strange symptoms– which I’d been told were “just pregnancy” lasted six months. No one could figure out what was wrong with me, why I couldn’t make stairs, why I felt like I’d been shot with novocaine. I learned later from a book by Jane Hightower that these were all symptoms of mercury exposure. I guess I’m one of those susceptible people. No one in my family is getting the H1N1– no one even gets regular flu shots anymore, we all read labels.
If you are a pregnant mother, please do not take the H1N1 swine flu vaccine. Instead, do everything that you can do to avoid public places and make sure to wash your hands more than you usually would. Take extra large doses of immunity building vitamins and research many of the great natural ways for fighting the flu that are out there on the Internet.
The truth is that if you do take the vaccine and then something happens, you will NOT be able to sue anyone (thanks to Congress). You will have to bear all the responsibility yourself. That doctor who kept pushing and pushing it on you will tell you that it could not have been the vaccine and that you probably would have miscarried anyway.
Do you honestly want to inject a vaccine that may contain mercury, formaldehyde, polysorbate 80 (associated with infertility), triton X100 (a strong detergent), phenoxyethanol (antifreeze) and a whole bunch of other toxic ingredients into your system when you know that your baby will absorb it too and has no defenses against most of these things?
MYFOXNY.COM – It was a panicky scene at P.S. 124 in South Ozone Park, Queens, Monday when some students complained of headaches after getting the swine flu vaccination.
After one or two children said they felt sick, apparently more children swamped the nurse’s office, officials said.
The Health Department told Fox 5 that the school called 911 in an abundance of caution. Three children were taken to Jamaica Hospital for headaches, dizziness, and nausea. One of the children complaining of symptoms hadn’t even gotten the vaccine.
However, school and health officials point out that it is not uncommon for people to have minor reactions to any vaccination, including the swine flu shot.
http://www.myfoxny.com/dpp/health/swine_flu/091109-queens-schoolchildren-swine-flu-shots
Une femme de 42 ans est décédée mardi soir des complications de la grippe A(H1N1), en Montérégie.
La dame était en bonne santé, mais elle souffrait d’un problème d’asthme léger.
Elle avait été hospitalisée le 30 octobre dans un centre de la région puis transférée dans un hôpital montréalais. Les symptômes grippaux s’étaient manifestés la veille seulement.
La victime travaillait au service informatique de l’Hôpital Anna-Laberge de Châteauguay. Elle n’était toutefois pas en contact avec des patients.
Elle avait été vaccinée deux jours avant son hospitalisation, mais l’immunité du vaccin se développant au cours des 10 premiers jours après avoir reçu la dose, elle n’était pas protégée.
Il s’agit du premier décès relié au virus dans cette région depuis le début de la deuxième vague de la grippe. Au cours des deux derniers mois, 132 personnes ont été hospitalisées en Montérégie, dont 13 dans un état jugé sévère.
C’est le troisième décès à survenir au Québec depuis le 30 août. Une femme de 85 ans de Québec et une autre de 26 ans de Gatineau ont également été foudroyées par la grippe A(H1N1).
(sources: Gouvernement du Québec, LCN)
http://matin.branchez-vous.com/nouvelles/2009/11/h1n1_deces_en_monteregie.html
Vanliga:
o Ömhet, rodnad och smärta vid injektionsstället och i armen.
o Influensasymtom av typen feber, frossa, trötthet.
o Huvudvärk av lite kraftigare karaktär.
o Värk i kroppen och allmän sjukdomskänsla.
Mindre vanliga:
o Illamående.
o Kräkningar.
o Magont.
o Diarré.
o Yrsel.
o Utslag.
o Sömnlöshet.
Sällsynta:
o Påverkan av nervsystemet genom att antikroppar som bildas också angriper kroppens egen nervvävnad. Det kan leda till tillfällig förlamning, som i de allra flesta fall går tillbaka med eller utan behandling.
Hur många som drabbats:
o Mer än 200 rapporter om biverkningar har lämnats in till läkemedelsverket. Ytterligare 500 rapporter har lämnats in av privatpersoner.
o 37 patienter har fått allergiska reaktioner som bedömts haft en koppling till vaccinet.
15 av dem har ansetts vara allvarliga.
o Totalt är det drygt 20
rapporter om allvarliga biverkningar som kommit in till läkemedelsverket.
Kommentar från Annika Linde, Smittskyddsinstitutet:
o ”Vi har inte sett några allvarliga biverkningar i någon högre grad hittills. Biverkningsgraden är som förväntat utifrån de förstudier som gjorts.”
Källa: Läkemedelsverket och vårdguiden.
Du som är sjuk:
o Du som har en pågående infektionssjukdom, exempelvis med feber eller luftvägsinfektion, ska vänta med vaccineringen tills några dagar efter att du har blivit frisk.
Du som är mycket allergisk mot ägg:
o Om du kan vaccinera dig
eller inte beror på hur allergisk du är. Din läkare kan bedöma om du kan vaccineras eller inte. Det finns ett annat typ av vaccin, Celvapan, som inte köpts in till Sverige. Det innehåller inga tillsatser och är ett cellbaserat vaccin vilket innebär att även äggallergiker kan ta det.
Du som har lämnat prov och vet säkert att du redan haft svininfluensan:
o Om du inte har lämnat prov kan du inte veta helt säkert om du haft svininfluensan och rekommenderas därför att vaccinera dig. Du som har lämnat prov och fått bekräftat att du haft svininfluensan är immun och behöver inte vaccinera dig. Det är inte farligt att
ta vaccinet även om du redan har haft svininfluensan.
Källa: Vardguiden.se
Så många dagar/ veckor tar det innan du har fullt skydd.
o En till två veckor. Det kan vara individuellt, vissa har snabbare immunsystem än andra.
Dröjer det olika länge för olika grupper?
o För de som har haft en likartad influensa tidigare, framför allt äldre människor, går det snabbare att bygga upp immunförsvaret. Då har man en grundimmunitet att bygga vidare på.
o För barn tar det längre tid. Kroppen börjar reagera på vaccinet omgående, men man har inte ett fullgott skydd förrän efter ungefär två veckor.
Hur vanligt är det att man får svininfluensa efter vaccin?
o Man kan smittas under de första dagarna, men i nuläget finns inga uppgifter på hur
vanligt det är. Enligt Annika Linde kan vi dock räkna med att många kommer att insjukna
efter det att de fått vaccinet men innan det hunnit verka och ger fullgott skydd.
Hur länge är man skyddad?
o Vanligt influensavaccin ger skydd i nio månader. Det här vaccinet anses vara bättre men man vet inte exakt hur länge det ger skydd. Tester ska göras för att följa hur antikroppsnivåerna sjunker och utifrån det ska längden på skyddet avgöras.
Hur säkert är skyddet?
o Mer än 95 procent. Det är en jättebra siffra, för det finns inget vaccin som egentligen ger ett hundraprocentigt skydd efter en spruta.
Källa: Annika Linde, Smittskyddsinstitutet.
Vilka grupper behöver ta två doser?
o Barn 3–12 år. De har inte mött liknande virus tidigare och har inget immunförsvar för detta.
o De som tillhör riskgruppen med sänkt immunförsvar, de som till exempel har hiv eller får cellgifter. Två doser behövs på grund av det nedsatta immunförsvaret.
Vilka grupper behöver inte ta en andra dos?
o Gravida.
o Friska från 13 år och uppåt.
o Riskgruppspatienter med friskt immunförsvar.
Vid vilken tidpunkt ska man ta andra dosen?
o Det ska gå minst tre veckor mellan det första och andra vaccinationstillfället. Under den tiden hinner immunförsvaret landa ordentligt. Man kan vänta längre tid innan man tar den andra dosen, upp till sex månader.
Källa: Annika Linde, Smittskyddsinstitutet.
http://www.expressen.se/Nyheter/1.1772492/sa-paverkas-din-kropp-av-vaccinet
Normally people do not drop dead after taking a vaccine. More commonly, the adverse effects of taking a vaccine take a while to show up, as only later victims develop autism, dementia, neurological disorders, paralysis, infertility or cancer (among a wide variety of other conditions). However, numerous reports are now coming in from all over Europe of people becoming seriously ill and even dropping dead after getting injected with the H1N1 swine flu vaccine.
*In Sweden, there have been over 350 reported serious adverse reactions to the H1N1 swine flu vaccine, and there have been five people who have died there after taking the vaccine. Reportedly there is now a media blackout on reporting any additional deaths from the swine flu vaccine as the authorities do not want to discourage people from getting the vaccine.
*In Northern Ireland, a 15-year-old boy fell seriously ill and was on the verge of death less than 24 hours after receiving the swine flu vaccine.
*A 64 year old woman in Hungary recently dropped dead two days after she received the swine flu vaccine.
*The Flu Case website is reporting on other deaths from the swine flu vaccine in Europe, but so far those reports have not been confirmed.
In addition, on our sister site Bird Flu Pandemic, our readers have been reporting numerous horror stories regarding the swine flu vaccine…..
Pina:
my daughter is a nurse. She was at another clinic as a patient one day after H1N1 vaccines started. The staff there let her know that one man collapsed after getting the shot. A nurse that she went to school with had the vaccine and her arm went partially paralyzed. The feeling came back into her arm slightly and now she is in sheer pain. Don’t get the H1N1 shot, or flu shots if you haven’t.please.
Ann:
My friend was diagnosed w/GBS today. She had the H1N1 vaccine on Tuesday. She woke up friday morn. with one side of her face paralized, now almost her whole face is paralized. She is starting blood and plasma transfusions tonight. She will be transferred to Barnes hospital soon for more extensive testing. To those who laugh at the severity of this strange, unknown sickness and vaccine I hope you stay informed and not ignorant.
Carrie:
I am a healthcare employee…..the only vaccine offered to employees was the live vaccine. I decided to get it and be the “guinea pig” instead of my toddler. Received the nasal spray on Tuesday, woke up Wednesday with a sore throat and stuffy nose, Thursday had a terrible chest congestion/cough with fever and splitting headache, Friday all symptoms were worse and I couldn’t breathe! I was diagnosed on Friday with H1N1 and pneumonia….. good thing I got the vaccine, huh?
The reality is that the swine flu vaccine is untested and unsafe. The vaccine manufacturers have been given blanket immunity by Congress so you cannot sue them if something goes wrong. There are going to be many more serious side effects and many more deaths from the swine flu vaccine. Make sure that your family is not the next vaccine horror story.
WARSAW, Poland – Polish Prime Minister Donald Tusk said Friday that his government won’t buy vaccines for swine flu that have not been properly tested or from producers who won’t take responsibility for possible side effects.
Tusk told reporters that vaccine producers were pressuring governments to buy, but were also demanding that all responsibility and compensation for possible negative side effects fall upon government shoulders.
“Today we are dealing with great pressure from pharmaceutical firms … we are dealing with expectations that hundreds of millions of zlotys (dollars) will be spent on vaccine while no one wants to guarantee that it has no side effects,” he said.
He stressed that the few dozen swine cases in Poland have been mild and no deaths have been reported.
Some independent health experts have been advising vaccination after a recent surge in flu cases in neighbouring Ukraine saw more than 700,000 cases and 109 deaths of people with flu-like illness in recent weeks.
Fourteen of the fatalities were swine flu cases, Polish news agency PAP reported, citing Ukraine’s chief doctor Oleksandr Bilovol.
Polish health officials said a military medical laboratory in Pulawy was testing samples taken in Ukraine from sick people. Poland is also sending face masks to Ukraine.
On Thursday, the World Health Organization said that the swine flu virus has become the predominant flu strain worldwide.
In some countries, swine flu accounts for up to 70 per cent of the flu viruses being sampled, according to Dr. Keiji Fukuda, WHO’s top flu official.
While most people recover from the illness without needing medical treatment, officials are also continuing to see severe cases in people under 65 – people who are not usually at risk during regular flu seasons.
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